LiverChipTM is a dynamic 3-D cell culture platform which exactly mimics the architecture and physiology of the human liver.
LiverChipTM products and services are sold and used for drug metabolism and toxicity testing in pharmaceutical drug discovery.
Enabling the study of cellular behaviour and function in a much more in vivo-like environment by combination of 3-D cellular organization, co-culture of different liver cell types and liquid flow through the system
Opening up a much longer time window to study low clearance compounds and drug-drug interactions
Providing high value data sets on a smaller number of compounds at the “lead optimization” stages of drug discovery
Providing responses which more closely replicate human clinical responses
Replacing the use of animals in testing
Reducing risk of future late stage clinical trial failures by identifying unsafe drugs and through selection of the most efficacious candidates earlier in development
Enabling more cost efficient drug development meaning that new medicines can be brought to market more quickly